Showing posts with label Drug Discovery. Show all posts
Showing posts with label Drug Discovery. Show all posts
Monday, September 28, 2015

Scientists identify new agent to combat tuberculosis

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(Griselimycin) Above pic: The protein forms a homodimeric ring (shown as blue cartoon & surface representation). Each...
Friday, September 25, 2015

Once-weekly Trulicity 0.75 mg shows promising results in Japanese patients with type 2 diabetes

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In continuation of my update on  dapagliflozin Results from a new study of Japanese patients with type 2 diabetes showed once-we...
Monday, September 14, 2015

Promising preliminary results for AKB-9778 in diabetic macular oedema

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AKB-9778, a small molecule competitive inhibitor of vascular endothelial-protein tyrosine phosphatase (VE-PTP), has a good safety and ef...
Tuesday, September 8, 2015

Study expands understanding of the production of ET-743 compound

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In continuation of my update on  Trabectedin For decades, scientists have known that ET-743, a compound extracted from a marine inv...
Monday, August 31, 2015

Chemical compound shows promise in treating rheumatoid arthritis

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Montana State University researchers and their collaborators have published their findings about a chemical compound that shows ...
Tuesday, August 25, 2015

First-line axitinib ‘feasible’ in advanced, metastatic RCC

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We know that, Axitinib (AG013736; trade name Inlyta) is a small molecule tyrosine kinase inhibitor developed by Pfizer. It has bee...
Wednesday, August 12, 2015

Potential new painkiller provides longer lasting effects ..........

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Medications have long been used to treat pain caused by injury or chronic conditions. Unfortunately, most are short-term fixes or...
Monday, April 20, 2015

Designed Molecules Trap Cancer Cells in Deadly Cages

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Chemists have designed a carbohydrate-based molecule that can surround and strangle bone cancer cells by self-assembling into a tangle...
Thursday, March 19, 2015

New version of common antibiotic could eliminate risk of hearing loss

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"All I remember is coming out of treatment not being able to hear anything," said Bryce, now a healthy 14-year-old living in Ari...
Tuesday, March 17, 2015

Honey offers new approach to fighting antibiotic resistance ............

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In continuation of my update on Honey.. Honey, that delectable condiment for breads and fruits, could be one sweet solution to t...
Friday, March 13, 2015

Can-Fite BioPharma completes RA Phase III study of lead drug candidate CF101

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Can-Fite BioPharma Ltd.  a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and...
Tuesday, March 10, 2015

Final Phase 1 data of zoptarelin doxorubicin Phase 1/2 trial published in Clinical Cancer Research

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Aeterna Zentaris Inc. (NASDAQ: AEZS, TSX: AEZ) (the "Company")  announced that an article on final data for the Phase 1 po...
Sunday, February 1, 2015

SLU researcher discovers new information about how antibiotics stop staph infections

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In research published in  Proceedings of the National Academy of Sciences , assistant professor of biochemistry and molecular biology at...
Friday, January 16, 2015

Cimetidine drug could be one of many common over-the-counter medicines to treat cancer...

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    We know that,  Cimetidine  is a histamine  H 2 -receptor antagonist  that inhibits  stomach  acid production. It is largely used in...
Wednesday, December 31, 2014

Basilea reports granting of U.S. orphan drug designation to isavuconazole for the treatment of invasive candidiasis

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In continuation of my up date on isavuconazole Isavuconazole  ( BAL4815 ) is an experimental  triazole  antifungal. Its  prodrug...
Wednesday, December 24, 2014

Experimental anti-cancer drugs PF-04691502 and PD-0325901 excel against colorectal cancer models

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Genes make proteins and proteins tell your body's cells what to do: one talks to the next, which talks to the next, and to the n...
Friday, December 5, 2014

Chemotherapy drug combined with cancer-killing virus may treat recurrent ovarian cancer

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In continuation of my update on  doxorubicin In six out of 10 cases, ovarian cancer is diagnosed when the disease is advanced an...
Monday, December 1, 2014

New anti-cancer drug may protect normal cells against radiation

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Although radiation treatments have become much more refined in recent years, it remains a challenge to both sufficiently dose the tu...
Friday, November 21, 2014

FDA Approves Olysio (simeprevir) in Combination with Sofosbuvir for Genotype 1 Chronic Hepatitis C Infection

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In continuation of my update on sofosbuvir Janssen Therapeutics, Division of Janssen Products, LP (Janssen) announced the U.S. Food ...
Thursday, October 30, 2014

VAL-083 drug compound shows promise against non-small cell lung cancer

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We know that, VAL-083 is a bi-functional alkylating agent; inhibit U251 and SF188 cell growth in monolayer better than TMZ and caused ...