Med-Chemist

Med-Chemist : "Quintessential Medicinal Chemistry"

Showing posts with label BRAF kinase activity. Show all posts
Showing posts with label BRAF kinase activity. Show all posts
Wednesday, June 8, 2011

Positive results from Plexxikon's vemurafenib Phase 2 and 3 trial against metastatic melanoma

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We know that, PLX-4032(RG7204, Vemurafenib) is a highly selective inhibitor of BRAF kinase activity, with an IC50 of 44 nmol/L against V600...
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