Monday, March 31, 2014

New drug multiplies analgesic effect of opioids without increasing constipation

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Systemic (subcutaneous) or local (intraplantar) treatment of wild-type mice with the selective  σ 1  antagonists BD-1063 [1-[2-(3,4-di...
Monday, March 17, 2014

New research raises hopes of new class of drugs to combat antibiotic resistant infections

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New research raises hopes of new class of drugs to combat antibiotic resistant infections
Wednesday, March 12, 2014

Rotaxanes make symmetry history | Chemistry World

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A UK team has stumbled upon  an efficient way to separately produce each member of an unusual mirror image pair of chemical systems that h...
Monday, March 10, 2014

Caffeine-based compound with small amount of gold could be used as anticancer agent

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The side effects of ingesting too much caffeine - restlessness, increased heart rate, having trouble sleeping - are well known, but re...
Friday, March 7, 2014

Triphase's marizomib receives FDA orphan drug designation for treatment of multiple myeloma

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Salinosporamide A  (Marizomib) is a potent  proteasome inhibitor  used as an  anticancer agent  that recently entered phase I human  clini...
Thursday, March 6, 2014

Astellas Pharma to exclusively commercialize isavuconazole in the U.S. and Canada

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Isavuconazole (BAL4815)  is a  triazole  antifungal. Its prodrug, isavuconazonium sulfate (BAL8557) is currently in two Phase IIIclinica...
Sunday, March 2, 2014

Researchers discover novel treatments for psoriasis that are likely to cause fewer side effects

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In the article in  Science Translational Medicine , which features Juan Guinea-Viniegra as the lead author, the authors state that: "bl...
Friday, February 28, 2014

Adocia reports positive preliminary results for first clinical trial of BioChaperone Combo

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Adocia reports positive preliminary results for first clinical trial of BioChaperone Combo
Friday, February 21, 2014

FDA Accepts Filing of NDA for IV Antibiotic Oritavancin with Priority Review

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FDA Accepts Filing of NDA for IV Antibiotic Oritavancin with Priority Review Oritavancin  ( INN , also known as  LY333328 ) is a novel semi-...
Wednesday, February 19, 2014

Small molecules stop cervical cancer virus assembling

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Researchers in China have  disrupted the life cycle of the leading cause of cervical cancer  – the human papilloma virus – using a macrocy...
Tuesday, February 18, 2014

Old FDA-approved drugs may hold promise for treatment of rare, drug-resistant cancer

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After studying how samples of GIST responded to various concentrations of the 89 drugs in the laboratory, Dr. Duensing and her colleagues ...
Monday, February 17, 2014

Researchers create promising compound for cancer treatment

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Researchers create promising compound for cancer treatment
Sunday, February 16, 2014

FDA-approved drug pregabalin effectively treats RLS symptoms with less side effects

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In continuation of my update on pregabalin A report in the Feb. 13  New England Journal of Medicine  confirms previous studies sugges...
Wednesday, February 5, 2014

Melatonin shows potential to slow tumor growth in certain breast cancers

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An    early stage study shows melatonin   a hormone that regulates the body's sleep and awake cycles  may have the potential to help s...
Tuesday, February 4, 2014

Geranium extracts inhibit HIV-1

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Extracts of the geranium plant Pelargonium sidoides inactivate human immunodeficiency virus type 1 (HIV-1) and prevent the virus from inv...