Friday, November 30, 2012

Diabetes drug rosiglitazone, improves memory, study suggests

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In continuation of my update on  rosiglitazone   Working with genetically engineered mice designed to serve as models for Alzheimer...
Tuesday, November 27, 2012

New drug, regorafenib overcomes resistance in patients with rare sarcoma, study suggests

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I n continuation of my update on  regorafenib A new targeted drug demonstrated its ability to control metastatic gastrointestinal str...
Monday, November 26, 2012

Potential role of green tea catechins in various disease therapies: Progress and promise Mak 2012 Clinical and Experimental Pharmacology and Physiology Wiley Online Library

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Potential role of green tea catechins in various disease therapies: Progress and promise Mak 2012 Clinical and Experimental Pharmacology...
Sunday, November 25, 2012

Positive results from Genentech Avastin plus temozolomide Phase III study on glioblastoma

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Positive results from Genentech Avastin plus temozolomide Phase III study on glioblastoma : Genentech, a member of the Roche Group, today ...
Saturday, November 24, 2012

CLR01 effectively inhibits synaptotoxicity in mice with Alzheimer's

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We know that, aggregation of α-synuclein (α-syn) is implicated as being causative in the pathogenesis of Parkinson’s disease, multipl...
Friday, November 23, 2012

Natural product produced by marine algae shows promise in stroke recovery treatment

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A new study using brevetoxin-2 (see structure), a compound produced naturally by marine algae, stimulated nerve cell growth and plas...
Thursday, November 22, 2012

Drug shrinks brain tumors in children with tuberous sclerosis complex, study suggests

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In continuation of my update on   Everolimus   "Every patient in this study experienced a decrease in size of their tumo...
Wednesday, November 21, 2012

Smart drug improves survival in older patients with acute myeloid leukemia

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Gemtuzumab ozogamicin (marketed by Wyeth as Mylotarg ) is a drug-linked monoclonal antibody that was used to treat acute myelogenous leuk...
Tuesday, November 20, 2012

Drug trio of rapamycin, sildenafil and doxorubicin improved effectiveness of cancer treatment, protected heart

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Combining cancer medication with a drug for erectile dysfunction and one for heart transplants helped kill cancer cells and protected the...
Monday, November 19, 2012

Breast cancer drug, geldanamycin could halt other tumors

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The drug, geldanamycin , is well known for attacking a protein associated with the spread of breast cancer. However, a laboratory-based st...
Sunday, November 18, 2012

New targeted therapy for advanced prostate cancer shows anti-tumour activity in phase I clinical trials

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Researchers lead by Prof. Daniel Petrylakwill reports that,  a new drug that specifically targets a protein found on the surface of prostat...
Saturday, November 17, 2012

Cinacalcet failure raises trial conduct issues.....

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We know that, Cinacalcet (see above structure) is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissue...

Drinking green tea with starchy food may help lower blood sugar spikes

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In continuation on my update on green tea Mice fed an antioxidant found in green tea  epigallocatechin -3-gallate, or EGCG  ...
Friday, November 16, 2012

Metformin more effective than sulfonylurea in controlling type 2 diabetes

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In continuation of my update on Metformin A Vanderbilt study examining the impact of the two most commonly prescribed oraldiabetes me...
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Thursday, November 15, 2012

Scientists show how sorafenib can be dangerous to the heart..

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In continuation of my update on  sorafenib Studying mice with the equivalent of a heart attack, researchers found that the drug sor...