Med-Chemist

Med-Chemist : "Quintessential Medicinal Chemistry"

Tuesday, October 30, 2012

Dulaglutide Fares Well in New Trials

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Eli Lilly and Co.'s potential once-weekly treatment for type 2 diabetes fared better than three other drugs in lowering blood sugar...
Monday, October 29, 2012

Bayer Releases Riociguat Data

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We  know that,   Riociguat  ( BAY 63-2521, below structure ) is a novel drug that is currently in clinical development by  Bayer . It is a...
Sunday, October 28, 2012

FDA Clears Eisai’s Epilepsy Drug Fycompa

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We know that,  Fycompa (see structure, perampanel) is a selective, non-competitive AMPA receptor antagonist discovered by the research...
1 comment:
Saturday, October 27, 2012

Inhibitory Effect of Carob (Ceratonia siliqua) Leaves Methanolic Extract on Listeria monocytogenes - Journal of Agricultural and Food Chemistry (ACS Publications)

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We know that,  Ceratonia siliqua , commonly known as the   Carob tree   and   St John's-bread ,     is a species of   floweringevergre...
Friday, October 26, 2012

Positive Results from Phase 2 Trial of Oral Calcitonin | News | Drug Discovery and Development Magazine

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Tarsa Therapeutics Inc. announced that a Phase 2 trial of its oral recombinant salmon calcitonin in the prevention of postmenopausal osteo...
Thursday, October 25, 2012

T-DM1 Extends Overall Survival | News | Drug Discovery and Development Magazine

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We know that, Trastuzumab emtansine (INN, also called trastuzumab-DM1 or trastuzumab-MCC-DM1 , abbreviated T-DM1 ) is an antibody-dru...
Tuesday, October 23, 2012

FDA Approves Oxtellar...

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Oxtellar  XR  is Oxcarbazepine Extended-Release Tablets... We know that,  Oxcarbazepine    is an  anticonvulsant  and  mood stabilizi...

Astex Begins Phase 2 Cancer Trial | News | Drug Discovery and Development Magazine

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Astex Begins Phase 2 Cancer Trial of  SGI-110 | News | Drug Discovery and Development Magazine
Monday, October 22, 2012

Empagliflozin Lowers Blood Pressure | News | Drug Discovery and Development Magazine

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We know that, Empagliflozin (see structure) is a SGLT2 inhibitor which is being investigated in clinical trials for the oral treatment ...
3 comments:
Saturday, October 20, 2012

Aveo Files Tivozanib NDA | News | Drug Discovery and Development Magazine

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We know that,  Tivozanib  (see structure below, AV-951) is an oral VEGF receptor tyrosine kinase inhibitor. It is undergoing clinical tria...
Friday, October 19, 2012

Cherry intake reduces risk of gout attacks

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In continuation of my update on cherries C herry intake reduces risk of gout attacks
Thursday, October 18, 2012

Synta announces results from ganetespib Phase 2b trial on NSCLC

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In continuation of my update on Ganetespib .... "The preliminary results from GALAXY indicate that the addition of ganetespib t...
1 comment:
Wednesday, October 17, 2012

Drug combinations show promise against metastatic melanoma

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In continuation of my update on V emurafenib .. A Phase I study in 44 patients shows that the combination of the MEK inhibitor GDC-0...
Tuesday, October 16, 2012

ARIAD announces initial results from AP26113 Phase 1/2 trial on non-small cell lung cancer

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We know that,  AP26113 (see structure) is a highly potent ALK inhibitor with IC50 of 0.62 nM. As an ALK inhibitor, AP26113 overcomes mu...
Sunday, October 14, 2012

Combination of targeted treatment drugs delays resistance in melanoma patients

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In continuation of my update on  dabrafenib and trametinib ..... Combination of targeted treatment drugs delays resistance in melanoma ...
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