Friday, December 30, 2011

Lostartan can reduce cigarette smoke-induced lung injury

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Researchers from Johns Hopkins University, BaltimoreLostartan, lead by have found that, Dr. Enid R. Neptune Losartan a drug used widely ...
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Thursday, December 29, 2011

MK 1775 shows promise against sarcomas..........

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   2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6- (4-(4-methyl- piperazin-1-yl)phenylamino)-1H-pyra -zolo [3,4-d]pyrimidin-3(2H)-...
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Wednesday, December 28, 2011

Oncolytics REOLYSIN-Gemzar combination Phase 2 pancreatic cancer clinical trial meets primary endpoint

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In continuation of my update on gemcitabine Oncolytics REOLYSIN-Gemzar combination Phase 2 pancreatic cancer clinical trial meets primary e...
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Tuesday, December 27, 2011

New Antibodies Treat Autoimmune Disease like Crohn's in Mice....

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  Synthetic drugs treat (below structure)  Crohn's disease in mice................. [zinc-binding motif (where X is any amino acid...
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Monday, December 26, 2011

Salk scientists develop new drug that improves memory and prevents brain damage in mice

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A new drug candidate may be the first capable of halting the devastating mental decline of Alzheimer's disease, based on the findings ...
Sunday, December 25, 2011

Notch inhibitor appears to treat breast cancer....

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In a novel therapeutic approach to treating breast cancer, Loyola University Medical Center researchers are reporting positive results ...
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Saturday, December 24, 2011

Zoledronic Acid Shows Long-Term Benefit in Survivorship for Premenopausal ER-Positive Breast Cancer

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In continuation of my update on Zoledronic acid.. .. Zoledronic Acid Shows Long-Term Benefit in Survivorship for Premenopausal ER-Positive...
Thursday, December 22, 2011

Scientists identify why African naked mole-rat feels no pain when exposed to acid

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In continuation of my update  naked mole-rat Scientists identify why African naked mole-rat feels no pain when exposed to acid : British r...
Tuesday, December 20, 2011

Drug Duo of Ixabepilone and sunitinib Kills Chemotherapy-resistant Ovarian Cancer Cells......

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In continuation of Sunitinib ... The use of two drugs never tried in combination before in ovarian cancer resulted in a 70 percent des...
Sunday, December 18, 2011

Geron Initiates Phase 2 Trial of GRN1005 in Brain Metastases from Breast Cancer

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In continuation of my update on Paclitaxel and drug discovery .... Geron Corporation, announced the initiation of GRABM-B ( GR N1005 A g...
Saturday, December 17, 2011

Drug combination highly effective for newly diagnosed myeloma patients......

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A three-drug combination treatment for the blood cancer multiple myeloma compares favorably to the best established therapy for newly dia...
Friday, December 16, 2011

Total Synthesis of Indolizidine (+)-223A :: ChemViews Magazine :: ChemistryViews

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Total Synthesis of Indolizidine (+)-223A :: ChemViews Magazine :: ChemistryViews

Synta's ganetespib shows potent in vitro and in vivo activity against multiple breast cancer types

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Synta researchers   have reported that, Ganetespib (structure)  shows potent in vitro and in vivo activity against multiple types of b...
Thursday, December 15, 2011

Combination of bortezomib and panobinostat shows promise against advanced multiple myeloma

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In co\continuation of  my update on Bortezomib... A phase 2 clinical trial has shown that pairing bortezomib with an experimental drug,...
Wednesday, December 14, 2011

Ruxolinitib reduces spleen size by 35% in patients with myelofibrosis

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In continuation of my ruxolinitib In a major advance in treatment, a multicenter study found that ruxolinitib did a better job than off-...