Med-Chemist

Med-Chemist : "Quintessential Medicinal Chemistry"

Sunday, February 28, 2010

Serotonin-Specific Reuptake Inhibitor (SSRIs) as antiinflammatory agents?

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We know that Selective serotonin reuptake inhibitors or serotonin-specific reuptake inhibitor ( SSRIs ) are a class of compounds typically...
Saturday, February 27, 2010

Bitter melon (gourd) extract inhibits breast cancer cell proliferation.....

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Momordica charantia (picture, source : wikipedia) is a tropical  and subtropical vine of the family Cucurbitaceae , widely grown for...
Friday, February 26, 2010

Closantel for treating river blindness ?

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Closantel ( see structure ) is a broad-spectrum salicylanilide  anthelmintic used as antitrematode, antinematodes and antiarthropo...
Thursday, February 25, 2010

New evidence that green tea may help fight glaucoma and other eye diseases

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In continuation of my update on green tea and its usefulness , I am sharing herewith this interesting article, where in the researchers clai...
Wednesday, February 24, 2010

New insight for design of novel antibiotic derivatives for drug resistant microorganisms...

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Viomycin and Capreomycin (a group of nonribosomal peptide antibiotics) belong to the tuberactinomycin (an essential component in the drug ...
Tuesday, February 23, 2010

New class of antibiotics with a novel mode of action (against drug resistant bacterii)

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Many Gram-negative bacteria have become multi-drug resistant in recent years, as they have developed mechanisms to escape the therape...
1 comment:
Monday, February 22, 2010

Researchers able to predict and reverse resistance to Sunitinib treatment....

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Van Andel Research Institute (VARI) researchers have found a way to  reverse resistance to Sunitinib ( see structure) , a treatment t...
Sunday, February 21, 2010

New strategy to overcome drug resistance (tamoxifen) in breast cancer ?

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A solution to tamoxifen resistance is sorely needed, and if a strategy like this can work, it would make a difference in our clinical ca...
2 comments:
Saturday, February 20, 2010

Positive phase II clinical results of abiraterone (for advanced prostate cancer)....

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We know that ,  Abiraterone (discovered and developed at the Institute of Cancer Research in London , see structure ) is a drug under i...
Friday, February 19, 2010

TB disease mechanism and the molecule to block It - discovered ......

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We know about the drug resistant tuberculosis and the havoc its causing, so there is an urgent need to  develop new drugs that can be useful...
Thursday, February 18, 2010

Latrepirdine (dimbon) may ease cognitive effects of Huntington's disease....

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We know that Dimebon (latrepirdine), an investigational drug currently in  Phase 3 development, that halt the onset of advanced Alzh...
1 comment:
Wednesday, February 17, 2010

FDA approves Olmesartan (Benicar, Olmetec) for children....

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Olmesartan ( Benicar , Olmetec-by Ranbaxy ) is an angiotensin II  receptor antagonist used to treat high blood pressure.   Mode...
Tuesday, February 16, 2010

Triapine with cisplatin a new standard of care for cervical cancer?

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In continuation of my update on cancer drug development,   I found this  info interesting to share with. Researchers  lead by Dr. Charl...
1 comment:
Monday, February 15, 2010

Enantioselective synthesis of Kinamycin F - a new hope for anticancer drug development ?

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The kinamycins are a series of naturally occurring compounds endowed with intriguing molecular architectures and potent biological prope...
Saturday, February 13, 2010

Denosumab exhibits superiority over Zometa in treatment of prostate cancer men with bone metastases

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Denosumab exhibits superiority over Zometa in treatment of prostate cancer men with bone metastases
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