Study reports anti-cancer activity in mice treated with experimental drug TAK-733
TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc.
Ref: http://www.heemd.com/news/?md=1510006/
http://www.medchemexpress.com/TAK-733.html
TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc.Ref: http://www.heemd.com/news/?md=1510006/
http://www.medchemexpress.com/TAK-733.html
