Showing posts with label Lenvima (lenvatinib) for Differentiated Thyroid Cancer. Show all posts
Showing posts with label Lenvima (lenvatinib) for Differentiated Thyroid Cancer. Show all posts

Monday, August 3, 2015

FDA Approves Lenvima (lenvatinib) for Differentiated Thyroid Cancer


LENVIMA (lenvatinib) Structural Formula Illustration



LENVIMA, a kinase inhibitor, is the mesylate salt of lenvatinib. Its chemical name is 4- [3chloro-4-(N’-cyclopropylureido)phenoxy]-7-methoxyquinoline-6-carbox- amide methanesulfonate. The molecular formula is C21H19ClN4O4•CH4O3S, and the molecular weight of the mesylate salt is 522.96. The chemical structure of lenvatinib mesylate is:

The U.S. Food and Drug Administration today granted approval to Lenvima(lenvatinib) to treat patients with progressive, differentiated thyroid cancer (DTC) whose disease progressed despite receiving radioactive iodine therapy (radioactive iodine refractory disease).

FDA Approves Lenvima (lenvatinib) for Differentiated Thyroid Cancer