Monday, October 28, 2013

Flumazenil reverses stress-triggered anxiety in methamphetamine dependant rats

We know that, Flumazenil (also known as flumazepil, code name Ro 15-1788, trade names Anexate, Lanexat, Mazicon, Romazicon) is abenzodiazepine receptor antagonist primarily available by injection only, and the only benzodiazepine receptor antagonist on the market today.
It was first introduced in 1987 by Hoffmann-La Roche under the trade name Anexate, but only approved by the FDA on December 20, 1991. Some years ago an oral preparation was under development,  though it had low bio-availability and was thus abandoned.

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