Sunday, November 1, 2009

Botox for Chronic Regional Pain Syndrome (CRPS). ...


We know that Botulinum toxin is a medication and a neurotoxic protein produced by the bacterium Clostridium botulinum, and is held to be the most toxic substance known to mankind with an LD50 of roughly 0.005-0.05 µg/kg. Despite its greatest known toxic effect, it is also used in very small doses to treat muscle spasms. The acceptance of BTX-A use for the treatment of spasticity and muscle pain disorders is growing, with approvals pending in many European countries and studies on headaches (including migraine), prostatic symptoms, asthma, obesity and many other possible indications are ongoing.

But some interesting findings of the same drug has been presented at the American Society of Plastic Surgeons (ASPS) Plastic Surgery 2009 conference, Oct. 23-27, in Seattle, i.e., botox can be used as a pain medication to fight Chronic Regional Pain Syndrome (CRPS).

The study found injecting Botox into the area affected by pain provides significant pain control. Eight patients suffering from severe pain received an average of nine injections , one every four weeks. All of patients reported a significant improvement (31.25 percent) in their daily pain control that was maintained for up to 17 months. Though the drug has been used to treat many problems like cervical dystonia (CD), strabismus, blepharospasm, primary axillary hyperhidrosis, glabellar lines (wrinkle fighter). this finding is more significant....

Ref : http://www.plasticsurgery.org/Documents/Media/ps2009/19-Botox-Chronic-Pain.pdf

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